Urinary exosomal microRNA-145-5p and microRNA-27a-3p act as noninvasive diagnostic biomarkers for diabetic kidney disease

Figure 3 Receiver operating characteristic curves of urinary exosomal miR-145-5p, miR-27a-3p and their combination to discriminate diabetic kidney disease from type 2 diabetes mellitus patients. The area under the curve for miR-27a-3p was 0.71 [95% confidence interval (CI): 0.547-0.871, P = 0.0239], 0.88 (95%CI: 0.784-0.985, P < 0.0001) for miR-145-5p, and 0.97 (95%CI: 0.927-1.000, P < 0.0001) for their combination. ROC: Receiver operating characteristic; AUC: Area under the curve.