Urinary exosomal microRNA-145-5p and microRNA-27a-3p act as noninvasive diagnostic biomarkers for diabetic kidney disease

Figure 1 The characterization of urinary exosome. A: The glomeruli histological features of diabetic kidney disease patients (Periodic acid-Schiff staining), Bar = 100 μm; B: The exosomal surface markers CD9, CD63 and TSG101 were detected by western blotting; C: The particle screenshots of nanoparticle tracking analysis (NTA) in the urine samples from participants; D: The diameter sizes and diameter concentration distributions of the particles were measured by NTA. NC: Normal control; DM: Diabetes mellitus; DKD: Diabetic kidney disease.