XB130 inhibits healing of diabetic skin ulcers through the PI3K/Akt signalling pathway

Figure 8 Knock-down of XB130 accelerated wound healing in diabetic mice via PI3K/Akt signalling pathway. A: Western blot analysis of AKT and p-AKT expression in each group; B: Quantification of Western blot results; C: Representative skin wound images from control and model mice at day 0, 7, and 14, model (n = 10), XB130-KD (n = 10), LY294002 (n = 10), XB130-KD + LY294002 (n = 10); D: HE and Masson staining of skin wound in each group. ^aP < 0.01, compared to the control group; ^bP < 0.05, compared to the XB130-KD group.