Network-pharmacology-based research on protective effects and underlying mechanism of Shuxin decoction against myocardial ischemia/reperfusion injury with diabetes

doi:10.4239/wjd.v14.i7.1057

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Jul 15, 2023 (publication date) through Feb 8, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jul 15, 2023; 14(7): 1057-1076
Published online Jul 15, 2023. doi: 10.4239/wjd.v14.i7.1057

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Figure 5 Protein-protein interaction network of targets related to Shuxin decoction for attenuating myocardial ischemia/reperfusion injury in diabetes. A: Protein-protein interaction (PPI) network of 58 targets generated by STRING 11.5; B: PPI network of 41 key therapeutic targets constructed via Cytoscape 3.9.0 software. In accordance with the degree value, the targets are organized in a descending order, ranging from the highest degree to the lowest degree.

Citation: Yang L, Jian Y, Zhang ZY, Qi BW, Li YB, Long P, Yang Y, Wang X, Huang S, Huang J, Zhou LF, Ma J, Jiang CQ, Hu YH, Xiao WJ. Network-pharmacology-based research on protective effects and underlying mechanism of Shuxin decoction against myocardial ischemia/reperfusion injury with diabetes. World J Diabetes 2023; 14(7): 1057-1076
URL: https://www.wjgnet.com/1948-9358/full/v14/i7/1057.htm
DOI: https://dx.doi.org/10.4239/wjd.v14.i7.1057