Copyright
©The Author(s) 2023.
World J Diabetes. Jul 15, 2023; 14(7): 1013-1026
Published online Jul 15, 2023. doi: 10.4239/wjd.v14.i7.1013
Published online Jul 15, 2023. doi: 10.4239/wjd.v14.i7.1013
Figure 5 Mechanisms of blood-retina-barrier dysfunction in diabetes mellitus.
AGEs: Advanced glycation end-products; Alk-1: Activin-like kinase receptor type I; BMP-9: Bone morphogenetic protein 9; IL-1: Interleukin 1 beta; P2X7: Purinergic receptor; PKC-: Protein kinase C beta; SFK: Src family of cytoplasmic proteins; TJ: Tight junction; TLR-4: Toll-like receptor 4; VEGF: Vascular endothelial growth factor; ZO-1: Zonula occludens 1.
- Citation: Robles-Osorio ML, Sabath E. Tight junction disruption and the pathogenesis of the chronic complications of diabetes mellitus: A narrative review. World J Diabetes 2023; 14(7): 1013-1026
- URL: https://www.wjgnet.com/1948-9358/full/v14/i7/1013.htm
- DOI: https://dx.doi.org/10.4239/wjd.v14.i7.1013