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World J Diabetes. May 15, 2023; 14(5): 549-559
Published online May 15, 2023. doi: 10.4239/wjd.v14.i5.549
Figure 1
Figure 1 Production of incretin and its benefits. Glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide produced in the pancreas and intestine mediated by prohormone convertase. The incretin hormones affect appetite and satiety, glucagon and insulin release, cardiovascular function, gastric emptying, triglycerides, and bone metabolism. GIP: Glucose-dependent insulinotropic polypeptide; GLP-1: Glucagon-like peptide-1; PC1/3: Prohormone convertase 1/3; PC2: Prohormone convertase 2.