Glucose metabolism continuous deteriorating in male patients with human immunodeficiency virus accepted antiretroviral therapy for 156 weeks

Table 2 Spearman correlation analysis of glucose metabolism parameters, general condition, anthropometric parameters, biochemical, immunological and virological indicators within 156 wk (n = 61)

	FPG		FINS		HOMA-IR		HOMA-β
	r	P value	r	P value	r	P value	r	P value
Age (yr)	0.120	0.008
NAFLD (0 = without, 1 = with)	0.155	0.001
Follow-up weeks			0.280	0.005
BMI (kg/m2)	0.291	0.004
Body fat percentage (%)	0.311	0.002
Body fat weight (kg)	0.297	0.003
Lean body mass weight (kg)	0.138	0.008
ALT (g/L)	0.126	0.006	0.221	0.031
AST (g/L)	0.081	0.029	0.352	< 0.0001
GGT (g/L)	0.127	0.005	0.230	0.025
ALP (g/L)	0.106	0.004	0.253	0.009	0.164	0.002
Cr (μmol/L)	0.198	< 0.0001			0.378	0.027
Cysc (mg/L)			-0.280	0.005
UA (mmol/L)					0.175	0.001	0.179	< 0.0001
CD3+ count (cells/μL)	-0.146	< 0.0001
CD4+count (cells/μL)	-0.107	0.030
CD8+count (cells/μL)	-0.120	0.002	-0.236	0.022	-0.121	0.026
CD3+%	-0.140	0.002
CD4+%			0.2363	0.023	0.111	0.042	0.118	0.030
CD8+%	0.134	0.007	-0.293	0.004
CD4+/CD8+			0.312	0.002
IgM (g/L)	-0.263	0.003
LV (copes/L)	-0.266	0.033	-0.374	0.045	-0.427	0.024
CD4+ count groups					-0.340	0.049

ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; Cr: Serum creatinine; Cysc: Serum cystatin C; FINS: Fasting insulin; FPG: Fasting plasma glucose; GGT: γ-Glutamyl transpeptidase; HOMA-IR: Homeostasis model assessment of insulin resistance; HOMA-β: Homeostasis model assessment of β cell function; IgM: Immunoglobulin M; NAFLD: Nonalcoholic fatty liver disease; UA: Uric acid; VL: Viral load.