Multiple influences of the COVID-19 pandemic on children with diabetes: Changes in epidemiology, metabolic control and medical care

doi:10.4239/wjd.v14.i3.198

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Mar 15, 2023; 14(3): 198-208
Published online Mar 15, 2023. doi: 10.4239/wjd.v14.i3.198

Table 2 Increase of the rate of diabetic ketoacidosis in patients with type 1 diabetes during the pandemic in studies led in different countries

Ref.	Country	COVID-19 period	No. patients	DKA (%)	Severe DKA (%)	Pre-COVID-19 period	No. patients	DKA (%)	Severe DKA (%)
Gera et al[37], 2021	Ohio (United States)	1 Mar-30 Jun, 2020	64	73¹	45^a	1 March-30 Jun, 2019	64	47¹	23^a
Rabbone et al[38], 2020	Italy	20 Feb-14 Apr, 2020	160	41.3	16.9¹	20 Feb-14 Apr, 2019	208	38.1	14.9¹
Goldman et al[39], 2022	Israel	15 Mar-30 June, 2020	146	58.2^a	19.9	15 Mar-30 Jun, 2017 15 Mar-30 Jun, 2018-15 Mar-30 Jun, 2019	120; 131; 113	44.2^a, 40.5^a, 38.9^a	9.2^a, 9.2^a, 13.3^a
Ng et al[40], 2020	United Kingdom	1 Mar-30 Jun, 2020	88	51	28	/	/	/	/
HO et al[42], 2021	Canada	17 Mar-31 Aug, 2020	107	68.2^a	27.1^a	17 Mar-31 Aug, 2019	114	45.6^a	13.2^a
Unsworth et al[43], 2020	United Kingdom	23 Mar-4 Jun, 2020	33	72.7	36.3	/	/	/	/
Cherubini et al[45], 2022	Italy	1 Jan-31 Dec, 2020	1169	39.6^a^,²	14.2^a^,²	2017-2019	3068	35.7^a	10.4^a

^aP value < 0.05.

¹P 0.03 for proportion of diabetic ketoacidosis (DKA) patients with severe DKA.

²In the text data are subdivided by periods of restrictions during COVID-19 pandemic.

DKA: Diabetic ketoacidosis; T1D: Type 1 diabetes; T2D: Type 1 diabetes.

Citation: Zucchini S, Scozzarella A, Maltoni G. Multiple influences of the COVID-19 pandemic on children with diabetes: Changes in epidemiology, metabolic control and medical care. World J Diabetes 2023; 14(3): 198-208
URL: https://www.wjgnet.com/1948-9358/full/v14/i3/198.htm
DOI: https://dx.doi.org/10.4239/wjd.v14.i3.198