Comparative study of type 2 diabetes mellitus-associated gut microbiota between the Dai and Han populations

Table 1 Subject demographics and biochemical blood indices

Parameter	Han population			Dai population
	Healthy adults, n = 8	T2DM patients, n = 12	Healthy children, n = 15	Healthy adults, n = 10	T2DM patients, n = 12	Healthy children, n = 10
Sex as male/female	3/5	8/4	7/8	5/5	9/3	4/6
Age in yr	50.63 ± 5.85	55.27 ± 11.76	5.00 ± 2.101	45.70 ± 14.662	55.92 ± 9.07	5.50 ± 1.183
FBG in mmol/L	4.85 ± 0.38	9.98 ± 5.891	3.23 ± 0.99	5.62 ± 1.36	7.74 ± 2.393	4.52 ± 0.29
HbA1c as %	5.55 ± 0.24	8.55 ± 2.591	5.23 ± 0.15	5.58 ± 0.19	7.24 ± 0.773,4	5.19 ± 0.35
TG in mmol/L	1.90 ± 0.63	2.22 ± 1.54	0.97 ± 0.241	3.90 ± 4.102	2.48 ± 1.91	1.12 ± 0.453
TC in mmol/L	5.15 ± 0.61	3.76 ± 1.451	4.01 ± 0.88	5.51 ± 1.04	4.85 ± 1.264	3.91 ± 0.573
HDL-C in mmol/L	1.28 ± 0.28	0.97 ± 0.221	1.48 ± 0.34	1.23 ± 0.28	1.26 ± 0.40	1.39 ± 0.42
LDL-C in mmol/L	3.12 ± 0.64	1.82 ± 0.711	2.16 ± 0.631	2.98 ± 1.23	2.75 ± 1.054	2.16 ± 0.38
APO-A1 in g/L	1.75 ± 0.27	1.30 ± 0.301	1.75 ± 0.36	1.83 ± 0.23	1.74 ± 0.374	1.61 ± 0.36
APO-B in g/L	1.04 ± 0.15	0.68 ± 0.181	0.72 ± 0.191	0.98 ± 0.24	0.94 ± 0.29	0.66 ± 0.093
WBC as 109/L	6.06 ± 1.44	6.41 ± 1.87	6.95 ± 1.11	6.79 ± 1.43	7.07 ± 2.09	8.32 ± 2.38
RBC as 1012/L	5.19 ± 0.66	4.82 ± 0.57	4.89 ± 0.27	5.09 ± 0.65	5.05 ± 0.57	4.90 ± 0.42
TBil in μmol/L	6.84 ± 1.59	14.19 ± 9.351	6.07 ± 4.48	8.71 ± 5.082	6.19 ± 1.984	5.74 ± 2.38
DBil in μmol/L	3.84 ± 0.79	6.31 ± 2.921	2.92 ± 2.34	3.96 ± 2.05	3.35 ± 1.024	3.13 ± 1.40
IBil in μmol/L	3.00 ± 0.85	7.88 ± 6.511	3.15 ± 2.28	4.75 ± 3.052	2.84 ± 1.344	2.61 ± 1.413
ALT in U/L	22.50 ± 11.33	31.36 ± 26.34	15.80 ± 14.85	25.50 ± 15.68	26.10 ± 17.22	13.70 ± 14.96
AST in U/L	21.13 ± 4.58	27.36 ± 25.61	31.50 ± 7.181	23.26 ± 8.71	23.14 ± 8.64	27.40 ± 6.45
GGT in U/L	34.75 ± 24.40	51.82 ± 90.65	9.67 ± 2.941	70.40 ± 66.342	38.67 ± 22.804	13.50 ± 8.153
BUN in mmol/L	5.63 ± 1.40	4.59 ± 1.70	3.68 ± 0.821	5.12 ± 1.51	5.23 ± 2.18	3.75 ± 0.91
Cr in μmol/L	70.38 ± 8.75	69.55 ± 20.92	32.17 ± 7.601	68.20 ± 17.69	85.50 ± 30.21	32.00 ± 4.003
Hcy in μmol/L	15.63 ± 3.45	12.35 ± 1.551	14.20 ± 3.12	13.59 ± 3.57	16.69 ± 3.474	11.55 ± 1.535
hs-CRP in mg/L	1.85 ± 3.35	3.46 ± 5.23	2.84 ± 6.665	1.84 ± 1.57	1.83 ± 1.474	0.47 ± 0.503

¹P < 0.05 vs healthy adults in the Han population.

²P < 0.05, healthy adults in the Han population vs healthy adults in the Dai population.

³P < 0.05 vs healthy adults in the Dai population.

⁴P < 0.05, adult type 2 diabetes mellitus patients in the Han population vs adult type 2 diabetes mellitus patients in the Dai population.

⁵P < 0.05, healthy children in the Han population vs healthy children in the Dai population.

ALT: Alanine transaminase; APO: Apolipoprotein; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; Cr: Creatinine; DBil: Direct bilirubin; FBG: Fasting blood glucose; GGT: Gamma glutamyl transferase; HbA1c: Hemoglobin A1c; Hcy: Homocysteine; HDL-C: High density lipoprotein cholesterol; hs-CRP: Hypersensitive C-reactive protein; IBil: Indirect bilirubin; LDL-C: Low density lipoprotein cholesterol; RBC: Red blood cell; T2DM: Type 2 diabetes mellitus; TBil: Total bilirubin; TC: Total cholesterol; TG: Triglyceride; WBC: White blood cell.