Reduced risk of dementia in patients with type 2 diabetes mellitus using Chinese herbal medicine: A nested case-control study

doi:10.4239/wjd.v14.i11.1632

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Nov 15, 2023; 14(11): 1632-1642
Published online Nov 15, 2023. doi: 10.4239/wjd.v14.i11.1632

Table 2 The association between dementia onset and use of Chinese herbal medicine among type 2 diabetes mellitus patients

CHM exposure	Patients				Crude OR (95%CI)	Adjusted OR¹ (95%CI)
CHM exposure	Cases, n = 11699		Controls, n = 11699		Crude OR (95%CI)	Adjusted OR¹ (95%CI)
Non-CHM users	9053	77.4	7533	64.4	¹	¹
CHM users	2646	22.6	4166	35.6	0.53 (0.50-0.56)	0.51 (0.48-0.53)
Low intensity (31-365 d)	2350	20.1	3366	28.8	0.58 (0.55-0.62)	0.57 (0.53-0.60)
Medium intensity (366-730 d)	206	1.8	482	4.1	0.35 (0.30-0.42)	0.33 (0.28-0.39)
High intensity (731 d or more)	90	0.8	318	2.7	0.24 (0.19-0.30)	0.22 (0.17-0.28)

¹Adjusted for potential confounders that contained age, residential area, monthly income and Charlson-Deyo comorbidity index.

CHM: Chinese herbal medicine; OR: odds ratio; CI: Confidence interval.

Citation: Liao HH, Livneh H, Huang HL, Hung JY, Lu MC, Guo HR, Tsai TY. Reduced risk of dementia in patients with type 2 diabetes mellitus using Chinese herbal medicine: A nested case-control study. World J Diabetes 2023; 14(11): 1632-1642
URL: https://www.wjgnet.com/1948-9358/full/v14/i11/1632.htm
DOI: https://dx.doi.org/10.4239/wjd.v14.i11.1632