Copyright
©The Author(s) 2023.
World J Diabetes. Oct 15, 2023; 14(10): 1502-1513
Published online Oct 15, 2023. doi: 10.4239/wjd.v14.i10.1502
Published online Oct 15, 2023. doi: 10.4239/wjd.v14.i10.1502
Category | Influence | ||
Prebiotic | Inulin | Decrease Firmicutes to Bacteroidetes ratio[22] | Improvement in Obesity |
Fructooligosaccharides | Increase Bifidobacterium[26] | Promotes gut health | |
Decrease expression of inflammatory cytokines | |||
Improved Insulin sensitivity | |||
Galactooligosaccharides | Increase Akkermansia mucinophila. Increase in Prevotella[27] | Intestinal barrier protection | |
Improved Insulin sensitivity | |||
Decrease inflammation | |||
Probiotic | Bifidobacterium | Increasing Akkermansia mucinophila[56] | Intestinal barrier protection |
Improved Insulin sensitivity | |||
Decrease inflammation | |||
Lactobacillus | Decreasing Firmicutes to Bacteroidetes ratio[57] | Improvement in Obesity | |
Postbiotic | Heat-killed Akkermansia mucinophila | Improves metabolic state in Obesity | |
Heat-inactivated Lactobacillus paracasei | Reduces the risk of pharyngitis, laryngitis, and diarrhea | ||
Heat-inactivated Bifidobacterium bifidum | Reduces symptoms of irritable bowel syndrome | ||
Butyrate (SCFA produced by the inactive microbe) | Increasing Lachnospiraceae[46] | Protection against diabetes and cardio-vascular diseases | |
Increasing Proteobacteria[46] | Increased gut mucus production | ||
Decreasing Clostridiaceae[46] | Increased gut barrier integrity |
- Citation: Antony MA, Chowdhury A, Edem D, Raj R, Nain P, Joglekar M, Verma V, Kant R. Gut microbiome supplementation as therapy for metabolic syndrome. World J Diabetes 2023; 14(10): 1502-1513
- URL: https://www.wjgnet.com/1948-9358/full/v14/i10/1502.htm
- DOI: https://dx.doi.org/10.4239/wjd.v14.i10.1502