Clopidogrel delays and can reverse diabetic nephropathy pathogenesis in type 2 diabetic db/db mice

Figure 6 Clopidogrel reduces renal macrophage infiltration in db/db mice. ^aP < 0.05 vs wild type mice; ^bP < 0.05 vs db/db mice. Immunohistochemical staining, magnification: × 400. A: Wild type; B: db/db mice; C: db/db + clopidogrel (20 mg/kg); D: Immunohistochemical analysis of F4/80 expression. WT: Wild type; db/db: db/db mice; Clo: Clopidogrel.