Copyright
©The Author(s) 2022.
World J Diabetes. Aug 15, 2022; 13(8): 643-653
Published online Aug 15, 2022. doi: 10.4239/wjd.v13.i8.643
Published online Aug 15, 2022. doi: 10.4239/wjd.v13.i8.643
Table 7 Association of rs1137101 with hypertension and type 2 diabetes mellitus (hypertension and hypertension + type 2 diabetes mellitus)
Model | Genotype | Han, n = 892 | Mongolian, n = 852 | ||||||
Control, n (%) | HTN with T2DM, n (%) | OR (95%CI) | P value | Control, n (%) | HTN with T2DM, n (%) | OR (95%CI) | P value | ||
Co-dominant | G/G | 312 (76.8) | 394 (81.1) | 1 | 0.034 | 436 (66.6) | 151 (76.7) | 1 | 0.0067 |
A/G | 91 (22.4) | 84 (17.3) | 0.65 (0.46-0.92) | 202 (30.8) | 42 (21.3) | 0.54 (0.36-0.81) | |||
A/A | 3 (0.7) | 8 (1.6) | 1.61 (0.41-6.28) | 17 (2.6) | 4 (2.0) | 0.55 (0.17-1.79) | |||
Dominant | G/G | 312 (76.8) | 394 (81.1) | 1 | 0.026 | 436 (66.6) | 151 (76.7) | 1 | 0.0016 |
A/G-A/A | 94 (23.1) | 92 (18.9) | 0.68 (0.49-0.96) | 219 (33.4) | 46 (23.4) | 0.54 (0.36-0.80) | |||
Recessive | G/G-A/G | 403 (99.3) | 478 (98.3) | 1 | 0.39 | 638 (97.4) | 193 (98.0) | 1 | 0.46 |
A/A | 3 (0.7) | 8 (1.6) | 1.77 (0.46-6.87) | 17 (2.6) | 4 (2.0) | 0.65 (0.20-2.11) | |||
Over-dominant | G/G-A/A | 315 (77.6) | 402 (82.7) | 1 | 0.012 | 453 (69.2) | 155 (78.7) | 1 | 0.0028 |
A/G | 91 (22.4) | 84 (17.3) | 0.65 (0.46-0.91) | 202 (30.8) | 42 (21.3) | 0.55 (0.37-0.82) | |||
Log-additive | - | - | - | 0.75 (0.55-1.02) | 0.067 | - | - | 0.59 (0.41-0.84) | 0.0024 |
- Citation: Zhao KY, Yuan ML, Wu YN, Cui HW, Han WY, Wang J, Su XL. Association of rs1137101 with hypertension and type 2 diabetes mellitus of Mongolian and Han Chinese. World J Diabetes 2022; 13(8): 643-653
- URL: https://www.wjgnet.com/1948-9358/full/v13/i8/643.htm
- DOI: https://dx.doi.org/10.4239/wjd.v13.i8.643