Association of rs1137101 with hypertension and type 2 diabetes mellitus of Mongolian and Han Chinese

Table 6 Association of rs1137101 with hypertension + type 2 diabetes mellitus (control vs hypertension + type 2 diabetes mellitus)

Model	Genotype	Han, n = 941				Mongolian, n = 650
		Control, n (%)	HTN with T2DM, n (%)	OR (95%CI)	P value	Control, n (%)	HTN with T2DM, n (%)	OR (95%CI)	P value
Co-dominant	G/G	351 (77.1)	394 (81.1)	1	0.0075	343 (75.7)	151 (76.7)	1	0.3
	A/G	94 (20.7)	84 (17.3)	0.59 (0.40-0.87)		101 (22.3)	42 (21.3)	0.70 (0.44-1.11)
	A/A	10 (2.2)	8 (1.6)	0.38 (0.14-1.08)		9 (2.0)	4 (2.0)	1.06 (0.27-4.25)
Dominant	G/G	351 (77.1)	394 (81.1)	1	0.0024	343 (75.7)	151 (76.7)	1	0.15
	A/G-A/A	104 (22.9)	92 (18.9)	0.56 (0.39-0.82)		110 (24.3)	46 (23.4)	0.72 (0.46-1.13)
Recessive	G/G-A/G	445 (97.8)	478 (98.3)	1	0.11	444 (98.0)	193 (98.0)	1	0.84
	A/A	10 (2.2)	8 (1.6)	0.43 (0.15-1.21)		9 (2.0)	4 (2.0)	1.15 (0.29-4.57)
Over-dominant	G/G-A/A	361 (79.3)	402 (82.7)	1	0.01	352 (77.7)	155 (78.7)	1	0.12
	A/G	94 (20.7)	84 (17.3)	0.61 (0.41-0.89)		101 (22.3)	42 (21.3)	0.70 (0.44-1.11)
Log-additive	-	-	-	0.60 (0.43-0.83)	0.0018	-	-	0.78 (0.52-1.16)	0.22

Adjusted for sex and age. P value of < 0.05 was considered significant. OR: Odd ratio; HTN: Hypertension; T2DM: Type 2 diabetes mellitus; CI: Confidence interval.