In vivo evaluation and mechanism prediction of anti-diabetic foot ulcer based on component analysis of Ruyi Jinhuang powder

doi:10.4239/wjd.v13.i8.622

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Aug 15, 2022 (publication date) through Feb 14, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Aug 15, 2022; 13(8): 622-642
Published online Aug 15, 2022. doi: 10.4239/wjd.v13.i8.622

Table 5 Docking parameters of chemical components and target protein molecules

Name	Target	LibDockScore
Luteolin	TOP2A	104.333
Methyl palmitate	PTGS2	114.221
ar-Turmeric	PTGS2	91.0625
ar-Turmeric	CHRM2	88.3765
Methyl Linoleate	RXRA	138.583
Methyl Linoleate	PTGS2	130.838
Palmitic acid	PTGS2	114.349
Demethoxycurcumin	PTGS2	135.479
Naringin	TOP2A	141.197
Naringin	PTGS2	164.305

PTGS2: Posttranscriptional silencing; TOP2A: Topoisomerase II alpha; CHRM2: Muscarinic acetylcholine receptor M2; RXRA: Retinoic X receptor alpha.

Citation: Li XY, Zhang XT, Jiao YC, Chi H, Xiong TT, Zhang WJ, Li MN, Wang YH. In vivo evaluation and mechanism prediction of anti-diabetic foot ulcer based on component analysis of Ruyi Jinhuang powder. World J Diabetes 2022; 13(8): 622-642
URL: https://www.wjgnet.com/1948-9358/full/v13/i8/622.htm
DOI: https://dx.doi.org/10.4239/wjd.v13.i8.622