Copyright
©The Author(s) 2022.
World J Diabetes. Apr 15, 2022; 13(4): 319-337
Published online Apr 15, 2022. doi: 10.4239/wjd.v13.i4.319
Published online Apr 15, 2022. doi: 10.4239/wjd.v13.i4.319
Figure 6 Insulin resistance and Alzheimer’s disease.
A: Amyloid beta (Aβ) relationship with insulin, the effect of Aβ plaques on insulin signaling, Aβ increases insulin resistance; B: Neuroinflammation and insulin inflammation disrupts insulin signaling pathways by impacting metabolic transducers. Some pictures were taken from Qiagen Pathways. Aβ: Amyloid beta; Pi3K: Phosphoinositide-3 kinase; Akt: Serine/threonine specific protein kinase; TNF-α: Tumor necrosis factor alpha.
- Citation: Ortiz GG, Huerta M, González-Usigli HA, Torres-Sánchez ED, Delgado-Lara DL, Pacheco-Moisés FP, Mireles-Ramírez MA, Torres-Mendoza BM, Moreno-Cih RI, Velázquez-Brizuela IE. Cognitive disorder and dementia in type 2 diabetes mellitus. World J Diabetes 2022; 13(4): 319-337
- URL: https://www.wjgnet.com/1948-9358/full/v13/i4/319.htm
- DOI: https://dx.doi.org/10.4239/wjd.v13.i4.319