Large-scale functional connectivity predicts cognitive impairment related to type 2 diabetes mellitus

Table 3 Classification outcome

Group	Brain atlas	AUC	Specificity	Sensitivity	P value
T2DM-NC vs T2DM-C	HOA-112 atlas	0.70	0.69	0.73	0.0144
	AAL-116 atlas	0.65	0.69	0.65	0.0556
	Power-264 atlas	0.70	0.63	0.77	0.0160
T2DM-NC vs HC	HOA-112 atlas	0.54	0.75	0.42	0.3122
	AAL-116 atlas	0.53	0.58	0.54	0.3804
	Power-264 atlas	0.56	0.58	0.58	0.2478
T2DM-C vs HC	HOA-112 atlas	0.54	0.63	0.56	0.3152
	AAL-116 atlas	0.72	0.67	0.75	0.0096
	Power-264 atlas	0.70	0.79	0.63	0.0184
T2DM vs HC	HOA-112 atlas	0.67	0.63	0.69	0.0144
	AAL-116 atlas	0.63	0.58	0.64	0.0444
	Power-264 atlas	0.50	0.50	0.67	0.4898

T2DM: Type 2 diabetes mellitus; T2DM-C/T2DM-NC: Patients with T2DM with the presence/absence of mild cognitive impairment; HC: Healthy controls; AUC: The area under the receiver operating characteristic curve; HOA-112: Harvard Oxford atlas; AAL-116: Automated Anatomical Labeling; Power-264: 264-region functional atlas introduced by Power et al.