Diabetes and COVID-19: Role of insulin resistance as a risk factor for COVID-19 severity

doi:10.4239/wjd.v12.i9.1550

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Sep 15, 2021; 12(9): 1550-1562
Published online Sep 15, 2021. doi: 10.4239/wjd.v12.i9.1550

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Figure 1 Insulin resistance may act as a bridging link between coronavirus disease 2019 and diabetes. The potential mechanism by which insulin resistance mediates coronavirus disease 2019 (COVID-19) severity is through angiotensin converting enzyme 2 protein, systemic inflammation, pancreatic β cell damage, and thrombosis. The potential markers of insulin resistance for evaluating diabetes status in patients with COVID-19 are also mentioned. CRP: C-reactive protein; CT: Computed tomography; IL-6: Interleukin-6; IR: Insulin receptor; MRI: Magnetic resonance imaging; T2DM: Type 2 diabetes mellitus.

Citation: Gangadharan C, Ahluwalia R, Sigamani A. Diabetes and COVID-19: Role of insulin resistance as a risk factor for COVID-19 severity . World J Diabetes 2021; 12(9): 1550-1562
URL: https://www.wjgnet.com/1948-9358/full/v12/i9/1550.htm
DOI: https://dx.doi.org/10.4239/wjd.v12.i9.1550