Association of β-cell function and insulin resistance with pediatric type 2 diabetes among Chinese children

Figure 3 Association of changes in the homeostasis model index with risk of type 2 diabetes by sex, obesity status, and puberty status. Error bars indicate 95%CIs. Red squares represent the association of per unit decrease in homeostasis model assessment of β-cell function z-score with type 2 diabetes mellitus (T2DM). Blue circles represent the association of per unit increase in homeostasis model assessment of insulin resistance z-score with T2DM. A: Age, Tanner stage, T2DM family history, body mass index (BMI) z-score, and lipid profile were adjusted; B: Sex, age, Tanner stage, T2DM family history, and lipid profile were adjusted; C: Sex, age, T2DM family history, BMI z-score, and lipid profile were adjusted. T2DM: Type 2 diabetes mellitus; HOMA2-%B: Homeostasis model assessment of β-cell function; HOMA2-IR: Homeostasis model assessment of insulin resistance.