Copyright
©The Author(s) 2021.
World J Diabetes. Aug 15, 2021; 12(8): 1146-1163
Published online Aug 15, 2021. doi: 10.4239/wjd.v12.i8.1146
Published online Aug 15, 2021. doi: 10.4239/wjd.v12.i8.1146
Figure 1 Mechanisms of action of short-chain fatty acids in type 2 diabetes mellitus.
The effect of short-chain fatty acids on energy metabolism is multidimensional, including appetite regulation, energy intake/expenditure, and lipid oxidation, as well as glucose metabolism. SCFA: Short-chain fatty acid; GLP-1: Glucagon-like peptide 1; PYY: Peptide YY; ER: Endoplasmic reticulum; UCP-1: Uncoupling protein-1; mTOR: Mammalian target of rapamycin.
- Citation: Xia F, Wen LP, Ge BC, Li YX, Li FP, Zhou BJ. Gut microbiota as a target for prevention and treatment of type 2 diabetes: Mechanisms and dietary natural products. World J Diabetes 2021; 12(8): 1146-1163
- URL: https://www.wjgnet.com/1948-9358/full/v12/i8/1146.htm
- DOI: https://dx.doi.org/10.4239/wjd.v12.i8.1146