Role of interferons in diabetic retinopathy

doi:10.4239/wjd.v12.i7.939

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jul 15, 2021; 12(7): 939-953
Published online Jul 15, 2021. doi: 10.4239/wjd.v12.i7.939

Table 1 Expression of interferons in samples

Source	Condition of disease	Expression
Tears	DR	(IFN-γ) ↑↑, (IFN-γ/MCP-1) ↓, (IFN-γ/IL-8) ↓[39]
Tears	DNR	(IFN-γ) ↑[39]
Aqueous humor	PDR	(IFN-γ) ↑↑[40]
	NPDR	(IFN-γ) ↑[40]
	DR	(IFN-γ) ↑↑[41], (IFN-α) ↓↓[117,118]
	DNR	(IFN-γ) ↑[41], (IFN-α) ↓[117,118]
Vitreous fluids	DR	(IFN-γ) ↑[42]
Vitreous fluids	DM	(IFN-γ) ↑[45]
Serum	DR	(IFN-γ) ↑↑[46]
	DNR	(IFN-γ) ↑[46]
	DM	(IFN-γ) ↑[47,48]
Plasma	DM	(IFN-α) ↑, (IFN-β) ↑[113]
Retina	DR	(IFN-β) ↑[115]

DR: Diabetic retinopathy; DNR: Diabetes without retinopathy; PDR: Proliferative diabetic retinopathy; NPDR: Non-proliferative diabetic retinopathy; DM: Diabetes mellitus; IFN: Interferons.

Citation: Li BY, Tan W, Zou JL, He Y, Yoshida S, Jiang B, Zhou YD. Role of interferons in diabetic retinopathy. World J Diabetes 2021; 12(7): 939-953
URL: https://www.wjgnet.com/1948-9358/full/v12/i7/939.htm
DOI: https://dx.doi.org/10.4239/wjd.v12.i7.939