Blood glucose response after oral lactulose intake in type 2 diabetic individuals

Table 3 Blood glucose endpoints: 30 g crystal lactulose vs water

	30 g crystal lactulose		Water		Treatment	P value
Variable	n	LS mean (95%CI)	n	LS mean (95%CI)	Difference (95%CI)
AUCbaseline_c (0-180 min) (min/mmol/L)	16	-30.70 (-76.75, 15.35)	16	-53.21 (-99.14, -7.28)	22.51 (-37.05, 82.06)	0.4529
AUC(0-180 min) (min/mmol/L)	16	1242.03 (1195.98, 1288.08)	16	1219.53 (1173.60, 1265.46)	22.51 (-37.05, 82.06)	0.4529
iAUC(0-180 min) (min/mmol/L)	16	27.65 (-3.91, 59.21)	16	18.44 (-13.04, 49.92)	9.21 (-34.39, 52.81)	0.6744
Cmax (mmol/L)	16	7.77 (7.44, 8.09)	16	7.44 (7.11, 7.77)	0.33 (-0.11, 0.76)	0.1426
Max_increase (mmol/L)	16	0.70 (0.37, 1.02)	16	0.37 (0.04, 0.70)	0.33 (-0.11, 0.76)	0.1426

AUC_{baseline_c (0-180 min)}: Baseline-corrected area under the curve from 0 to 180 min; AUC_{(0-180 min)}: Area under the curve from 0 to 180 min; iAUC_{(0-180 min)}: Incremental AUC_{(0-180 min)}, i.e., area above baseline levels of blood glucose concentration; C_max: Maximum blood glucose concentration; Max_increase: Maximum blood glucose concentration minus baseline value; LS mean: Adjusted least square mean obtained from analysis of covariance model.