Blood glucose response after oral lactulose intake in type 2 diabetic individuals

Table 2 Blood glucose endpoints: 20 g crystal lactulose vs water

	20 g crystal lactulose		Water		Treatment	P value
Variable	n	LS mean (95%CI)	n	LS mean (95%CI)	Difference (95%CI)
AUCbaseline_c (0-180 min) (min/mmol/L)	16	-54.40 (-100.23, -8.57)	16	-53.21 (-99.14, -7.28)	-1.20 (-60.78, 58.39)	0.9682
AUC(0-180 min) (min/mmol/L)	16	1218.33 (1172.50, 1264.16)	16	1219.53 (1173.60, 1265.46)	-1.20 (-60.78, 58.39)	0.9682
iAUC(0-180 min) (min/mmol/L)	16	17.00 (-14.43, 48.43)	16	18.44 (-13.04, 49.92)	-1.44 (-45.16, 42.29)	0.9478
Cmax (mmol/L)	16	7.50 (7.17, 7.82)	16	7.44 (7.11, 7.77)	0.06 (-0.38, 0.50)	0.7999
Max_increase (mmol/L)	16	0.43 (0.10, 0.75)	16	0.37 (0.04, 0.70)	0.06 (-0.38, 0.50)	0.7999

AUC_{baseline_c (0-180 min)}: Baseline-corrected area under the curve from 0 to 180 min; AUC_{(0-180 min)}: Area under the curve from 0 to 180 min; iAUC_{(0-180 min)}: Incremental AUC_{(0-180 min)}, i.e., area above baseline levels of blood glucose concentration; C_max: Maximum blood glucose concentration; Max_increase: Maximum blood glucose concentration minus baseline value; LS mean: Adjusted least square mean obtained from analysis of covariance model.