Control of modifiable risk factors and major adverse cardiovascular events in people with peripheral artery disease and diabetes

doi:10.4239/wjd.v12.i6.883

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 12, Issue 6

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (4394)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-3) series.

Item

Count

PDF

298

WORD

115

HTML

2255

Tables (1-3)

326

Sum=2994

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

435

Download

965

Sum=1400

Jun 15, 2021 (publication date) through Feb 21, 2025

Times Cited of This Article

Times Cited (5)

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Diabetes. Jun 15, 2021; 12(6): 883-892
Published online Jun 15, 2021. doi: 10.4239/wjd.v12.i6.883

Table 2 Association of peripheral artery disease-medical score with baseline characteristics

Risk factors	PAD-medical score				P value
Risk factors	*< 3.0 (n =* 106)**	*3-3.9 (n =* 145)**	*4.0-4.9 (n =* 140)**	*5.0 (n =* 33)**	P value
Age	65 (57-73)	70 (64-77)	69 (64-77)	70 (66-76)	0.002^b
Male sex	67 (63.2)	110 (75.9)	110 (78.6)	24 (72.7)	0.046^a
Aboriginal or Torres Strait Islander	3 (2.8)	9 (6.2)	4 (2.9)	3 (9.1)	0.242
Presenting problem					0.043^a
Carotid artery disease	12 (11.3)	19 (13.1)	27 (19.3)	5 (15.2)
Aortic or peripheral aneurysm	22 (20.8)	45 (31.0)	42 (30.0)	12 (36.4)
Lower limb ischemia	72 (67.9)	81 (55.9)	71 (50.7)	16 (48.5)
Smoking status					< 0.001^c
Current	55 (51.9)	41 (28.3)	5 (3.6)	0
Former	28 (26.4)	62 (42.8)	100 (71.4)	21 (63.6)
Never	22 (20.8)	42 (29.0)	35 (25.0)	12 (36.4)
IHD	38 (35.8)	64 (44.1)	75 (53.6)	24 (72.7)	0.001^b
Stroke	14 (13.2)	12 (8.3)	17 (12.1)	4 (12.1)	0.606
Medications
Aspirin	34 (32.1)	96 (66.2)	118 (84.3)	30 (90.9)	< 0.001^c
Other anti-platelet	11 (10.4)	25 (17.2)	41 (29.3)	7 (21.2)	0.002^b
Statins	58 (54.7)	115 (79.3)	121 (86.4)	30 (90.9)	< 0.001^c
Metformin	60 (56.6)	87 (60.0)	83 (59.3)	21 (63.6)	0.896
Other oral hypoglycemics	39 (36.8)	58 (40.0)	45 (32.1)	12 (36.4)	0.591
Insulin	26 (24.5)	35 (24.1)	33 (23.6)	4 (12.1)	0.482
HbA1c (%)	7.4 (6.8-8.7)	7.0 (6.5-7.7)	6.6 (6.0-7.6)	6.1 (5.9-6.4)	< 0.001^c
HDL-c (mmol/L)	1.1 (0.9-1.3)	1.1(0.9-1.3)	1.1(0.9-1.2)	0.9(0.8-1.2)	0.133
LDL-c (mmol/L)	2.60 (2.20-3.40)	2.10 (1.70-2.70)	1.60 (1.30-2.00)	1.34 (1.20-1.60)	< 0.001^c
SBP (mmHg)	150 (139-163)	139 (125-151)	135 (122-150)	126 (120-131)	< 0.001^c
C-reactive protein (mg/L)	3.0 (1.9-7.5)¹	2.0 (1.0-5.0)²	3.0 (1.0-5.6)³	2.1 (0.9-5.0)⁴	0.082
Major cardiovascular events	23 (21.7)	27 (18.6)	32 (22.9)	7 (21.2)	0.845

^aP < 0.05.

^bP < 0.01.

^cP< 0.001.

Data are presented as number (percentage) or median (interquartile range). C-reactive protein data is missing from 9¹, 15², 8³ and 5⁴ participants. PAD: Peripheral artery disease; IHD: Ischemic heart disease; HbA1c: Hemoglobin A1c; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; SBP: Systolic blood pressure.

Citation: Golledge J, Drovandi A, Rowbotham S, Velu R, Quigley F, Jenkins J. Control of modifiable risk factors and major adverse cardiovascular events in people with peripheral artery disease and diabetes. World J Diabetes 2021; 12(6): 883-892
URL: https://www.wjgnet.com/1948-9358/full/v12/i6/883.htm
DOI: https://dx.doi.org/10.4239/wjd.v12.i6.883