Copyright
©The Author(s) 2021.
World J Diabetes. Apr 15, 2021; 12(4): 306-330
Published online Apr 15, 2021. doi: 10.4239/wjd.v12.i4.306
Published online Apr 15, 2021. doi: 10.4239/wjd.v12.i4.306
Figure 1 Generation of transgenic-mini pigs carrying a dominant-negative mutant HNF1α gene.
A: Common domestic pig; B: Transgenic (Tg)-mini pigs carrying a dominant-negative mutant HNF1α gene; C: Body weights at specified times; D: Blood glucose level. Blue line: Common domestic pigs, n = 2-4. Orange line: Tg-mini pig, n = 1. Gray line: micro-mini pig, n = 2-4. Quantitative data are presented as means. Scale bar: 30 cm. Time after birth is indicated in days.
- Citation: Nagaya M, Hasegawa K, Uchikura A, Nakano K, Watanabe M, Umeyama K, Matsunari H, Osafune K, Kobayashi E, Nakauchi H, Nagashima H. Feasibility of large experimental animal models in testing novel therapeutic strategies for diabetes. World J Diabetes 2021; 12(4): 306-330
- URL: https://www.wjgnet.com/1948-9358/full/v12/i4/306.htm
- DOI: https://dx.doi.org/10.4239/wjd.v12.i4.306