Role of ferroptosis in the process of diabetes-induced endothelial dysfunction

Figure 5 Detection of xCT (the substrate-specific subunit of system Xc^-) and p53 expression in the aorta of db/db mice. A: The localization of xCT was detected by immunofluorescence. xCT is labeled red, and CD31 is labeled green. The nucleus is labeled blue. Scale bar: 100 μm; B and C: The messenger ribonucleic acid levels of p53 and xCT in mice aorta were determined using real-time polymerase chain reaction analyses. β-actin was used for normalization. ^aP < 0.05 vs the control group. ^bP < 0.01 vs the control group.