Risk factors for intraocular metastasis of primary liver cancer in diabetic patients: Alpha-fetoprotein and cancer antigen 125

doi:10.4239/wjd.v12.i2.158

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Feb 15, 2021 (publication date) through Feb 21, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Feb 15, 2021; 12(2): 158-169
Published online Feb 15, 2021. doi: 10.4239/wjd.v12.i2.158

Table 2 Differences in the concentration of various tumor biomarkers between patients with and without intraocular metastasis

Clinical features	IOM group	NIOM group	t	P value
AFP	1030.37 ± 342.38	526.37 ± 587.16	-5.17	< 0.001
CEA	6.54 ± 14.75	389.37 ± 10012.62	0.138	0.89
CA125	419.78 ± 356.43	148.03 ± 305.88	-3.165	0.002
CA199	200.35 ± 329.82	314.22 ± 4482.59	0.092	0.927
CA153	19.81 ± 15.06	20.32 ± 23.28	0.078	0.938
CA724	6.68 ± 8.44	6.91 ± 12.32	0.066	0.947
FER	198.23 ± 52.50	259.43 ± 224.57	0.981	0.327
ALP	192.54 ± 94.07	174.15 ± 171.39	-0.386	0.7
TC	4.75 ± 1.20	5.14 ± 8.62	0.161	0.872
TG	1.44 ± 0.81	1.37 ± 1.03	-0.257	0.797
HDL	1.30 ± 0.64	1.50 ± 1.17	0.602	0.548
LDL	2.52 ± 1.16	2.58 ± 1.43	0.144	0.885
ApoA1	1.65 ± 0.45	1.57 ± 0.87	-0.331	0.741
ApoB	0.77 ± 0.32	1.10 ± 0.82	1.426	0.154
Lp(a)	181.92 ± 219.72	221.66 ± 240.54	0.591	0.555
Ca	14.56 ± 44.90	2.14 ± 0.27	-0.997	0.338
Hb	114.69 ± 43.54	117.19 ± 22.31	0.207	0.84

P < 0.05 represents statistical significance. IOM: Intraocular metastasis; NIOM: Non-intraocular metastasis; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen; CA: Cancer antigen; FER: Ferritin; ALP: Alkaline phosphatase; TC: Total cholesterol; TG: Triglyceride; HDL: High density lipoprotein; LDL: Low density lipoprotein; ApoA1: Apolipoprotein A1; ApoB: Apolipoprotein B; Lp(a): Lipoprotein A; Ca: Calcium; Hb: Hemoglobin.

Citation: Yu K, Tang J, Wu JL, Li B, Wu SN, Zhang MY, Li QY, Zhang LJ, Pan YC, Ge QM, Shu HY, Shao Y. Risk factors for intraocular metastasis of primary liver cancer in diabetic patients: Alpha-fetoprotein and cancer antigen 125. World J Diabetes 2021; 12(2): 158-169
URL: https://www.wjgnet.com/1948-9358/full/v12/i2/158.htm
DOI: https://dx.doi.org/10.4239/wjd.v12.i2.158