Plasma melatonin levels in patients with diabetic retinopathy secondary to type 2 diabetes

Table 2 Multiple logistic regression analysis of the association between clinical characteristics and diabetic retinopathy/proliferative diabetic retinopathy risk

	DR		PDR
	Multivariate OR (95%CI)	P value	Multivariate OR (95%CI)	P value
Age (10 yr)	0.03 (0.008 to 0.063)	0.134	0.939 (0.003 to 0.011)	0.005
Diabetes duration(1 yr)	0.032 (0.025 to 0.039)	< 0.001	0.007 (0.007 to 0.023)	0.002
Hypertension	-0.023 (-0.105 to 0.059)	0.577	0.015 (-0.129 to 0.022)	< 0.001
BMI	-0.008 (-0.019 to 0.001)	0.090	-0.053 (-0.023 to -0.001)	0.166
Smoking	-0.033 (-0.109 to 0.044)	0.402	-0.012 (-0.098 to 0.075)	0.032
Drinking	-0.023 (-0.096 to 0.050)	0.532	-0.012 (-0.143 to 0.021)	0.791
FBG (mg/dL)	0.002 (0.001 to 0.003)	< 0.001	-0.061 (0.001 to 0.004)	0.143
HbA1C (%)	0.017 (-0.002 to 0.036)	0.084	0.002 (-0.006 to 0.037)	< 0.001
Total bilirubin (mmol/L)	0.004 (-0.006 to 0.014)	0.428	0.015 (-0.016 to 0.006)	0.158
Melatonin (pg/mL)	-0.008 (-0.010 to -0.005)	< 0.001	-0.005 (-0.004 to 0.002)	0.412

FBG: Fasting blood glucose; BMI: body mass index; HbA1C: Hemoglobin A1C.