Inhibitory effect of maspinon neovascularization in diabetic retinopathy

Figure 1 Retinal neovascularization was determined by counting the vascular cell nuclei (arrow) breaking through the inner limiting membrane on postnatal day 17. A: No nuclei were detected in the normal control group; B, C: There were many pathologic neovascular tufts beyond the inner limiting membrane (ILM) in the oxygen-induced retinopathy (OIR) group; D, E: Fewer vascular cell nuclei broke through the ILM in the maspin injection OIR group than in the OIR group but more than that in the normal control group. Magnification ×400; F: Data are means ± SD. ^bP < 0.01 vs normal control group; ^cP < 0.001 vs normal control group; ^dP < 0.01 vs the OIR group. OIR: Oxygen-induced retinopathy.