Copyright
©The Author(s) 2021.
World J Diabetes. Dec 15, 2021; 12(12): 2058-2072
Published online Dec 15, 2021. doi: 10.4239/wjd.v12.i12.2058
Published online Dec 15, 2021. doi: 10.4239/wjd.v12.i12.2058
Table 3 List of gene related to Kallmann syndrome and normosmic hypogonadotropic hypogonadism
Disease | Gene (Phenotype MIM number) | Count |
Kallmann syndrome and normosmic hypogonadotropic hypogonadism | FGFR1(147950), FGF8 (612702), PROK2 (610628), CHD7 (612370), WDR11 (614858) | 5 |
Normosmic hypogonadotropic hypogonadism | LEP (614962), LEPR (614963), NR0B1 (300200), SRA1, GNRHR (146110), GNRH1 (614841),KISS1R (614837), KISS1 (614842), TACR3 (614840), TAC3 (614839), NR5A1, HESX-1, LHX3, SOX2, FSHB (229070), LHB (228300), PC1, PNPLA6 (215470), RNF216, OTUD4, STUB1, POLR3A (607694), POLR3B (614381), RAB3GAP1, RAB3GAP2, RAB18, TBCID20, DMXL2, KISS1R(614837), NDNF (618841) | 30 |
Kallmann syndrome | ANOS1 (308700), FGF17 (615270), IL17RD (615267), DUSP6 (615269), SPRY4 (615266), FLRT3 (615271),, KLB, PROKR2 (244200), SEMA3A (614897), SEMA3E, SOX10, HS6ST1 (614880), CCDC141, FEZF1 (616030), IGSF10, SMCHD1, NELF (614838), SOX3 | 18 |
- Citation: Sun SS, Wang RX. Molecular diagnosis of Kallmann syndrome with diabetes by whole exome sequencing and bioinformatic approaches. World J Diabetes 2021; 12(12): 2058-2072
- URL: https://www.wjgnet.com/1948-9358/full/v12/i12/2058.htm
- DOI: https://dx.doi.org/10.4239/wjd.v12.i12.2058