Association between admission hemoglobin level and prognosis in patients with type 2 diabetes mellitus

Table 2 Threshold effect analysis of hemoglobin levels on the composite endpoint using piecewise linear regression

Cutoff point of hemoglobin level (K)	Hazard ratio (95%CI)1	P value
< 13.3 g/dL	0.58 (0.42-0.79)	0.0007
≥ 13.3 g/dL	1.63 (0.83-3.20)	0.1585

¹Adjusted for (model 4): Age, gender, body mass index, baseline estimated glomerular filtration rate, history of hypertension, systolic blood pressure, diastolic blood pressure, 24-h urinary protein, angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers use, albumin, total cholesterol, triglycerides, duration of diabetes, fasting glycaemia, and glycosylated hemoglobin.

A 13.3 g/dL threshold for the hemoglobin level existed for risk of the composite endpoint.