Diabetes-induced changes in cardiac voltage-gated ion channels

doi:10.4239/wjd.v12.i1.1

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Jan 15, 2021 (publication date) through Nov 5, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jan 15, 2021; 12(1): 1-18
Published online Jan 15, 2021. doi: 10.4239/wjd.v12.i1.1

Table 2 Changes in L-type Ca²⁺ and Na⁺ currents in diabetic heart myocytes

Diabetes Mellitus Type	Duration	Ca²⁺ currents	Ref.	Na⁺ currents		Ref.
Diabetes Mellitus Type	Duration	I_CaL	Ref.	I_Na	I_Na,L	Ref.
Type 1	≤ 4 wk	↔	[50]	↔	?	[130]
	4-8 wk	↓↔	[29,99,101-103,108]	↓	?	[130,132]
	> 8 wk	↓↔	[52,98]	↔↓	?	[69]
Type 1 transgenic		↓	[104]	?	↑	[135]
Type 2		↓	[89,105-108]	?	↑	[135]

Citation: Ozturk N, Uslu S, Ozdemir S. Diabetes-induced changes in cardiac voltage-gated ion channels. World J Diabetes 2021; 12(1): 1-18
URL: https://www.wjgnet.com/1948-9358/full/v12/i1/1.htm
DOI: https://dx.doi.org/10.4239/wjd.v12.i1.1