Analysis of long noncoding RNA-associated competing endogenous RNA network in glucagon-like peptide-1 receptor agonist-mediated protection in β cells

Figure 5 Co-expression network of long noncoding RNAs and hub mRNAs. A: Venn diagram of co-expressed long noncoding RNAs (lncRNAs) with Pomc, Htr2a, and Agtr1a. A co-expression network was constructed based on the Pearson coefficient with the filter condition as P value < 0.05 and |R| > 0.90. Twenty-one common lncRNAs were obtained by intersecting the co-expressed lncRNAs of Pomc, Htr2a, and Agtr1a. B: The 21 common lncRNAs co-expressed with Pomc, Htr2a, and Agtr1a, including 11 downregulated and 10 upregulated lncRNAs. Red circles represent upregulated lncRNAs, whereas the green circles represent downregulated lncRNAs.