Lack of Syndecan-1 produces significant alterations in whole-body composition, metabolism and glucose homeostasis in mice

Figure 4 O₂ consumption and energy expenditure throughout light in syndecan-1 knockout and wild type mice on high-fat diet. Like chow-diet, mice were fed with high-fat diet and all parameters were monitored as previously. Data represents mean ± SE of total 12 animals of each genotype. Statistical analysis was performed using the two-tailed student’s t-test. ^cP < 0.001. Sdc1 KO: Sdc1 knockout; HFD: High-fat diet; WT: Wild type.