Vitamin C ameliorated cardiac autonomic neuropathy in type 2 diabetic rats

Table 2 Markers of oxidative stress and inflammation

Markers	Control	Diabetic	VC treated
MPO (µmol/mL/mg protein)	1.63 ± 0.3	2.3 ± 0.07a	1.62 ± 0.31
NO (M/dL)	9.5 ± 0.3	20.1 ± 0.6b	8.7 ± 1.11
SOD (unit SOD/min)	0.7 ± 0.1	1.4 ± 0.04b	0.6 ± 0.11
LPO (nmol/mg protein)	8.1 ± 1.0	16.4 ± 1.2b	8.6 ± 0.71
GSH (mg/dL)	11.3 ± 1.0	5.89 ± 0.8b	9.2 ± 1.91
AA (µg/mL)	61 ± 10.6	39.2 ± 2.0b	62.3 ± 6.21

Results are mean ± SE, n = 10;

¹No significant difference from control;

^aP < 0.05,

^bP < 0.01, significantly different from control. MPO: Myeloperoxidase; NO: Nitric oxide; SOD: Super oxide dismutase; MDA: Malondialdehyde; GSH: Glutathione; AA: Ascorbic acid.