Exenatide once weekly combined with metformin reduced glycemic variability in type 2 diabetes by using flash glucose monitoring system

Table 3 Parameters of glycemic variability at baseline and 12 wk [mean ± SD or median (interquartile range)]

Variable		Baseline	12 wk	P value
SDBG (mmol/L)		2.8 ± 0.8	2.3 ± 0.6	0.017
CV (%)		26.3 ± 5.4	26.3 ± 3.5	0.997
MAGE (mmol/L)	Overall	5.7 ± 1.3	4.5 ± 1.1	0.006
	During day	5.8 ± 1.2	4.6 ± 1.3	0.010
	At night	4.7 ± 1.8	3.6 ± 1.2	0.020
MODD (mmol/L)	Overall	2.8 ± 1.2	1.6 ± 0.4	0.000
	During day	2.9 ± 1.1	1.8 ± 0.5	0.001
	At night	1.8 (1.1-3.9 )	1.0 (0.6-1.5 )	0.007
LAGE (mmol/L)	Overall	15.2 ± 2.6	13.5 ± 3.2	0.092
	During day	14.8 ± 2.8	13.1 ± 3.3	0.127
	At night	9.7 ± 3.6	8.5 ± 2.4	0.258
AUC of IQR		5017.5 ± 1932.8	3877.1 ± 1001.1	0.024
AUC of IDR		9713.2 ± 2782.2	8015.9 ± 2208.2	0.036

AUC of IDR: Area under the curve between percentiles 10 and 90; AUC of IQR: Area under the curve between percentiles 25 and 75; CV: Coefficient of variation; LAGE: Large amplitude of glycemic excursion; MAGE: Mean amplitude of glycemic excursion; MODD: Mean of daily difference; SDBG: Standard deviation of blood glucose.