Copyright
©The Author(s) 2020.
World J Diabetes. Nov 15, 2020; 11(11): 527-539
Published online Nov 15, 2020. doi: 10.4239/wjd.v11.i11.527
Published online Nov 15, 2020. doi: 10.4239/wjd.v11.i11.527
Table 2 Autoimmune diseases with corresponding autoantigens and tissue
AID | Tissue | Antigen |
Hashimoto’s thyroiditis | Thyroid enzyme/protein | Thyroid peroxidase/thyroglobulin |
Graves’ disease | Thyrocytes | TSH receptor |
Hypogonadism | Gonads, Leydig-/theca cells | 17-hydroxylase, cytochrome-P450 side-chain cleavage |
Addison disease | Adrenal cortex enzyme | 21-hydroxylase, cytochrome-P450 side-chain cleavage |
Hypoparathyroidism | Parathyroid | Ca2+ sensitive receptor |
Type A gastritis | Parietal cells | H+, K+-ATPase |
Vitiligo | Melanocytes | Tyrosinase |
Celiac disease | Small intestine | Transglutaminase, gliadin |
Neurodermatitis | Skin | IgE receptor |
Psoriasis | Skin | Keratin |
Alopecia | Hair follicles | Tyrosine hydroxylase |
Urticaria | Skin | IgE receptor FcERI, immunoglobulin E |
Sjögren’s Syndrome | Salivary glands | SS-A/Ro and SS-B/La |
Rheumatoid arthritis | Synovial membrane | CCP |
Autoimmune hepatitis | Liver cells | Smooth muscle, liver-kidney-microsome, soluble liver antigen, liver-pancreas antigen |
Systemic lupus erythematosus | Skin, vascular connective tissue | Double-stranded DNA |
Crohn’s disease | Gastrointestinal tract | Microbial antigens |
- Citation: Frommer L, Kahaly GJ. Type 1 diabetes and associated autoimmune diseases. World J Diabetes 2020; 11(11): 527-539
- URL: https://www.wjgnet.com/1948-9358/full/v11/i11/527.htm
- DOI: https://dx.doi.org/10.4239/wjd.v11.i11.527