Factors associated with improvement in waist-to-height ratio among newly diagnosed type 2 diabetes patients treated with acarbose or metformin: A randomized clinical trial study

Table 6 Association between changes in glucagon-like peptide 1 and a high change of waist-to-height ratio

	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Acarbose
AUCinsulin, μIU/L × min	0.897 (0.814 to 0.987)	0.027	0.922 (0.830 to 1.024)	0.127
AUCGLP-1, nmol × min	1.136 (1.044 to 1.237)	0.003	1.121 (1.022 to 1.230)	0.016
HDL-C/NHDL-C	17.934 (3.165 to 101.613)	0.001	20.735 (3.416 to 125.871)	0.001
Metformin
FPG, mmol/L	0.803 (0.687 to 0.938)	0.006	0.843 (0.717 to 0.992)	0.039
TC	0.707 (0.560 to 0.893)	0.004	0.743 (0.587 to 0.940)	0.013

AUC: Area under the curve; GLP-1: Glucagon-like peptide 1; HDL-C/non-HDL-C: HDL-C-to-non-HDL-C ratio; FPG: Fasting plasma glucose; TC: Total cholesterol.