Importance of serum phosphate in elderly patients with diabetes mellitus

doi:10.4239/wjd.v11.i10.416

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Oct 15, 2020; 11(10): 416-424
Published online Oct 15, 2020. doi: 10.4239/wjd.v11.i10.416

Table 1 The differences between groups of patients according to serum phosphate higher or lower than the cut-off point related to diabetes mellitus equal to 3.65 mg/dL

Characteristic	Patients with serum P > 3.65 mg/dL (n = 43), mean ± SD	Patients with serum P < 3.65 mg/dL (n = 67), mean ± SD	P value
Age (yr)	71.2 ± 12.8	67.6 ± 15.2	0.2
BMI (kg/m²)	30.2 ± 6.3^a	28.1 ± 4.6	0.04
WC (cm)	108.09 ± 15.9	102.8 ± 14.3	0.07
Uric acid (mg/dL)	6.7 ± 1.2^a	6.09 ± 1.7	0.05
LDL-C (mg/dL)	102.2 ± 29.5	110.1 ± 32.1	0.2
HDL-C (mg/dL)	44.5 ± 13.2	47.1 ± 9.8	0.2
Triglycerides (mg/dL)	137.7 ± 54.4	129.01 ± 60.1	0.4
Calcium (mg/dL)	9.5 ± 0.6	9.5 ± 0.5	0.9
P (mg/dL)	4.2 ± 0.4^a	3.2 ± 0.3	0.001
i-PTH (pg/mL)	mean rank = 68.06^a	47.4	0.001
25(OH)D3 (ng/mL)	18.9 ± 12.7	20.8 ± 9.2	0.3
Glucose (mg/dL)	mean rank = 63.6^a	50.28	0.03
Insulin (μU/mL)	11.6 ± 7.4	11.9 ± 8.7	0.8
HOMA-IR (mmol/L)	mean rank = 56.8	54.6	0.7
SBP (mmHg)	147.4 ± 16.7^a	140.2 ± 16.1	0.02
DBP (mmHg)	mean rank = 62.08	51.28	0.07
pMBP (mmHg)	108.02 ± 9.8^a	103.6 ± 7.8	0.01
PP (mmHg)	65.7 ± 16.2	61.01 ± 17.7	0.1
ACR (mg/g)	mean rank = 63.2^a	50.6	0.04
eGFR (mL/min/1.73 m²)	45.6 ± 22.1^a	55.4 ± 21.5	0.02
Category variables	n (%)	n (%)
DM (yes/no)	17 (39.5)/26 (60.5)^a	12 (17.9)/55 (82.1)	0.01
Hypertension (yes/no)	34 (79.1)/9 (20.9)^a	41 (61.2)/26 (38.8)	0.03
Receiving vitD (yes/no)	22 (51.2)/21 (48.8)^a	18 (26.9)/49 (73.1)	0.009
Smoking (yes/no)	10 (23.3)/33 (76.7)^a	4 (6)/63 (94)	0.01
Alcohol consumption (yes/no)	13 (30.2)/30 (69.8)	16 (23.9)/51 (76.1)	0.3
Physical activity (yes/no)	17 (39.5)/26 (60.5)	34 (50.7)/33 (49.3)	0.1
Classification based on eGFR:			0.04
eGFR > 90 mL/min/1.73 m²	3 (7)^a	6 (9)
eGFR = 60-90 mL/min/1.73 m²	7 (16.3)	18 (26.9)
eGFR = 30-60 mL/min/1.73 m²	21 (48.8)	37 (55.2)
eGFR = 15-30 mL/min/1.73 m²	12 (27.9)	6 (9)

^aP < 0.05. P: Phosphate; BMI: Body mass index; WC: Waist circumference; LDL-C: Low density lipoprotein cholesterol; HDL-C: High density lipoprotein cholesterol; i-PTH: Intact-parathyroid hormone; 25(OH)D₃: 25 hydroxyD₃; HOMA-IR: Homeostasis model assessment of insulin resistance; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; pMBP: Peripheral mean blood pressure; PP: Pulse pressure; ACR: Albumin-to-creatinine ratio; eGFR: Estimated glomerular filtration rate; DM: Diabetes mellitus.

Citation: Raikou VD, Kyriaki D, Gavriil S. Importance of serum phosphate in elderly patients with diabetes mellitus. World J Diabetes 2020; 11(10): 416-424
URL: https://www.wjgnet.com/1948-9358/full/v11/i10/416.htm
DOI: https://dx.doi.org/10.4239/wjd.v11.i10.416