Systematic Reviews
Copyright ©The Author(s) 2019.
World J Diabetes. Feb 15, 2019; 10(2): 114-132
Published online Feb 15, 2019. doi: 10.4239/wjd.v10.i2.114
Table 13 Change in homeostasis model assessment-estimated insulin resistance in individual studies
StudyHOMA-IR
P valueP value between groups
GroupBaselineStudy completion
Ito et al[12]Ipragliflozin5.2 (2.5)4.8 (5.5)Non-significant0.401
Pioglitazone5.7 (3.4)4.5 (2.7)< 0.05
Eriksson et al[14]Placebo4.2 (2.4)-0.2 (1.4)1--
Omega 3-CA5.4 (2.9)+0.3 (2.4)1-Non-significant2
Dapagliflozin4.3 (1.9)-1.1 (1.4)1-< 0.052
O + D4.4 (1.7)-0.9 (1.6)1-< 0.052
Seko et al[16]SGLT-2 inhibitor4.5 (0.5)7.9 (2.3)0.955-
Sitagliptin4.4 (0.5)6.5 (0.8)0.163