Relationship between sonographically measured median nerve cross-sectional area and presence of peripheral neuropathy in diabetic subjects

Table 5 Comparison of median nerve cross-sectional area between categories of age, gender, duration of diabetes mellitus, and glycemic control at carpal tunnel and 5 cm proximal to the carpal tunnel

		Median nerve CSA (mm2) at CATL
		DM_nonDPN	P-value	DM_DPN	P-value	HC	P-value
Duration of DM	≤ 5 yr	11.4 ± 1.8	0.65	12.9 ± 2.4	0.99	-	-
	> 5 yr	11.8 ± 3.3		12.9 ± 2.7		-
FBG	≤ 7 mmol/L	11.6 ± 2.3	0.79	13.2 ± 2.9	0.34	-	-
	> 7 mmol/L	11.4 ± 2.0		12.5 ± 1.8		-
HBA1c	≤ 7%	11.0 ± 1.8	0.45	12.3 ± 2.4	0.20	-	-
	> 7%	11.7 ± 2.3		13.2 ± 2.6		-
Age	≤ 60 yr	11.1 ± 1.9	0.25	12.9 ± 2.3	1.00	8.7 ± 1.5	0.37
	> 60 yr	12.0 ± 2.4		12.9 ± 2.7		8.4 ± 1.9
Sex	Female	11.3 ± 1.9	0.62	13.2 ± 2.6	0.42	8.1 ± 1.2	0.02
	Male	11.7 ± 2.4		12.6 ± 2.4		9.0 ± 2.0
		Median nerve CSA (mm2) at 5cmCATL
		DM_nonDPN	P-value	DM_DPN	P-value	HC	P-value
Duration of DM	≤ 5 yr	7.6 ± 1.9	0.87	7.7 ± 1.7	0.13	-	-
	> 5 yr	7.5 ± 1.5		8.5 ± 2.2		-
FBG	≤ 7 mmol/L	7.5 ± 1.3	0.74	8.2 ± 1.9	0.57	-	-
	> 7 mmol/L	7.7 ± 2.5		7.9 ± 2.0		-
HBA1c	≤ 7%	7.5 ± 1.4	0.86	7.7 ± 2.2	0.29	-	-
	> 7%	7.6 ± 1.9		8.3 ± 1.8		-
Age	≤ 60 yr	7.3 ± 1.5	0.32	8.4 ± 2.1	0.25	5.5 ± 1.2	0.79
	> 60 yr	7.9 ± 2.2		7.8 ± 1.8		5.4 ± 1.5
Sex	Female	7.0 ± 1.4	0.10	7.8 ± 1.7	0.37	4.9 ± 0.7	0.00
	Male	8.0 ± 2.0		8.3 ± 2.2		5.9 ± 1.6

CATL: Carpal tunnel; 5cmCATL: 5 cm proximal to the carpal tunnel; DM_nonDPN: Diabetics without diabetic peripheral neuropathy; DM_DPN: Diabetics without diabetic peripheral neuropathy; HC : Healthy controls. P values < 0.05 are significant.