Editorial
Copyright ©2010 Baishideng.
World J Diabetes. Mar 15, 2010; 1(1): 3-7
Published online Mar 15, 2010. doi: 10.4239/wjd.v1.i1.3
Table 1 Pharmacological profile of oral PDE5-i at therapeutic dosage for ED
ParameterSildenafil 100 mgTadalafil 20 mgVardenafil 20 mg
Tmax (h)1.16 ± 0.9920.66 (0.250-3.0)
T1/2 (h)3.82 ± 0.8417.53.94 ± 1.31
C (max ng/m)327 ± 23637820.9 ± 1.83
AUC (ng × h/m)1963 ± 859806674.5 ± 1.82