Extramural vascular invasion and response to neoadjuvant chemoradiotherapy in rectal cancer: Influence of the CpG island methylator phenotype

Table 4 Binary logistic regression analysis; extramural vascular invasion positivity against overall survival and other pathological, demographic and molecular features

	OR	95%CI (lower)	95%CI (upper)	P value
Overall survival	0.936	0.893	0.981	0.006
T stage	7.764	1.749	34.463	0.007
N stage	2.552	0.851	7.651	0.095
Age	1.024	0.969	1.081	0.405
Systemic recurrence	0.865	0.200	3.749	0.846
Sex	0.564	0.119	2.668	0.470
Local recurrence	1.841	0.193	17.562	0.596
Involved CRM	0.276	0.009	8.376	0.459
KRAS mutation	1.577	0.389	6.391	0.524
CIMP-H	6.368	1.091	37.162	0.040

CRM: Circumferential resection margin; CIMP: CpG island methylator phenotype.