Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature

doi:10.4251/wjgo.v9.i4.142

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Apr 15, 2017; 9(4): 142-152
Published online Apr 15, 2017. doi: 10.4251/wjgo.v9.i4.142

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Figure 1 Molecular classification of colorectal cancer. The figure shows the different molecular profile and clinic-histopathological characteristics of each classification. CIMP: CpG island methylator phenotype; MSI: Microsatellite instability; MS: Microsatellite stability; CRC: Colorectal cancer; CIN: Chromosomal instability; HNPCC: Hereditary nonpolyposis colorectal cancer; MGMT: O-6-methylguanine-DNAmethyltransferase; BRAF: v-raf murine sarcoma viral oncogene homologe B1; MLH1: MutL homolog 1; KRAS: Kirsten rat sarcoma 2 viral oncogene homolog; APC: Adenomatosis polyposis coli; TP53: Tumor protein p53.

Citation: Galanopoulos M, Tsoukalas N, Papanikolaou IS, Tolia M, Gazouli M, Mantzaris GJ. Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature. World J Gastrointest Oncol 2017; 9(4): 142-152
URL: https://www.wjgnet.com/1948-5204/full/v9/i4/142.htm
DOI: https://dx.doi.org/10.4251/wjgo.v9.i4.142