Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature

Table 1 DNA integrity index in colorectal cancer patients

Ref.	Increased DNA integrity	Decreased DNA integrity
Umetani et al[45], 2006	Yes	-
Da Silva Filho et al[46], 2013	Yes	-
Leszinski et al[47], 2014	Yes	-
Mouliere et al[48], 2011	-	Yes
Mead et al[49], 2011	-	Yes
Mouliere et al[50], 2014	-	Yes
Yörüker et al[51], 2015	-	Yes