CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies

doi:10.4251/wjgo.v9.i3.105

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Mar 15, 2017; 9(3): 105-120
Published online Mar 15, 2017. doi: 10.4251/wjgo.v9.i3.105

Table 2 Gastrointestinal adenocarcinoma types, sample sizes, probe set sizes, and CpG island methylator phenotype status

Cancer type	Differentially methylated probes	Control samples	Tumor samples	CIMP-	CIMPi	CIMP+
EAC	6717	11	87	26	31	30
STAD	1110	2	260	109	95	56
COAD	2656	38	274	96	92	86
READ	1255	7	96	31	39	26

CIMP: CpG island methylator phenotype; CIMPi: CIMP intermediate; COAD: Colon adenocarcinoma; EAC: Esophageal adenocarcinoma; READ: Rectal adenocarcinoma; STAD: Stomach adenocarcinoma.

Citation: Sánchez-Vega F, Gotea V, Chen YC, Elnitski L. CpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies. World J Gastrointest Oncol 2017; 9(3): 105-120
URL: https://www.wjgnet.com/1948-5204/full/v9/i3/105.htm
DOI: https://dx.doi.org/10.4251/wjgo.v9.i3.105