Paradoxical expression pattern of the epithelial mesenchymal transition-related biomarkers CD44, SLUG, N-cadherin and VSIG1/Glycoprotein A34 in gastrointestinal stromal tumors

Table 3 Correlation of the diagnostic biomarkers with the epithelial mesenchymal/mesenchymal epithelial transition -related factors SLUG, N-Cadherin, CD44 and V-set and immunoglobulin domain containing 1 in gastrointestinal stromal tumors

	n	SLUG				CD44				N-Cadherin				VSIG1
		-	+	OR (95%CI)	P	-	+	OR (95%CI)	P	-	+	OR (95%CI)	P	-	+	OR (95%CI)	P
Ki67 index
Low	60	9	51	7.56 (0.42-136.02)	0.16	39	21	1.23 (0.43-3.50)	0.68	55	5	1.94 (0.42-8.97)	0.4	9	51	0.70 (0.19-2.60)	0.6
High	20	0	20			12	8			17	3			4	16
C-KIT
Positive	74	9	65	1.88 (0.09-36.23)	0.67	47	27	0.87 (0.14-5.06)	0.87	66	8	0.60 (0.03-11.65)	0.73	11	63	0.34 (0.05-2.14)	0.25
Negative	6	0	6			4	2			6	0			2	4
DOG-1
Positive	61	7	54	1.10 (0.20-5.81)	0.11	37	24	0.55 (0.17-1.72)	0.3	54	7	0.42 (0.04-3.72)	0.44	6	55	0.18 (0.05-0.65)	0.01
Negative	19	2	17			14	5			18	1			7	12
C-theta
Positive	72	7	65	0.321 (0.05-1.91)	0.21	45	27	0.55 (0.10-2.95)	0.49	67	5	8.04 (1.47-43.81)	0.02	9	63	0.14 (0.03-0.67)	0.02
Negative	8	2	6			6	2			5	3			4	4

VSIG1: V-set and immunoglobulin domain containing 1.