Immunohistochemical analysis of the Wnt/β-catenin signaling pathway in pancreatic neuroendocrine neoplasms

Figure 3 Expression of E-cadherin and adenomatous polyposis coli in the pancreas and pancreatic neuroendocrine neoplasms (original magnification 200 ×). A: Strong membranous E-cadherin labeling in the exocrine pancreas and weak membranous E-cadherin labeling in pancreatic islets (black arrows); B: Weak membranous E-cadherin in one pancreatic neuroendocrine neoplasm; C: Expression of cytoplasmic APC by pancreatic islets (black arrows) but not by the exocrine pancreas; D: Cytoplasmic APC labeling in one pancreatic neuroendocrine neoplasm. APC: Adenomatous polyposis coli.