MicroRNA-320 family is downregulated in colorectal adenoma and affects tumor proliferation by targeting CDK6

Figure 1 MiRNA expression profiles of matched samples. A: Regions of colorectal carcinoma, pre-existing adenoma, and adjacent non-neoplastic mucosa in a resection specimen were microdissected using laser microdissection (LMD); B and C: The miRNA expression profiles were compared with three matched regions from LSTs (n = 3) and protruded tumors (n = 3). For each miRNA, red represents higher expression and green represents lower expression than the average expression. LST: Laterally spreading type; C: Carcinoma; A: Adenoma; N: Adjacent non-neoplastic mucosa.