Genetic risks and familial associations of small bowel carcinoma

doi:10.4251/wjgo.v8.i6.509

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Jun 15, 2016 (publication date) through Nov 30, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jun 15, 2016; 8(6): 509-519
Published online Jun 15, 2016. doi: 10.4251/wjgo.v8.i6.509

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Figure 1 Schematic drawing of genetic and molecular pathways predisposing to small bowel carcinoma. Wnt: Wingless-type MMTV integration site family; KRAS: Kirsten rat sarcoma viral oncogene homolog; LOH: Loss of heterozygosity; CIMP: CpG island methylator phenotype; MSI: Microsatellite instability; BRAFV600E: V-raf murine sarcoma viral oncogenes homolog B; mTOR: Mammalian target of rapamycin; TGF-β: Transforming growth factor β; IL: Interleukin; CD4TL: CD4 T-lymphocytes.

Citation: Shenoy S. Genetic risks and familial associations of small bowel carcinoma. World J Gastrointest Oncol 2016; 8(6): 509-519
URL: https://www.wjgnet.com/1948-5204/full/v8/i6/509.htm
DOI: https://dx.doi.org/10.4251/wjgo.v8.i6.509